Easy Steps to Prevent Mesothelioma

Mesothelioma is a rare cancer that attacks the body's mesothelial cells around the organs. The mesothelium provides a protective membranous lining for the internal organs and allows moving organs (i.e. the heart and the lungs) to glide easily against adjacent structures. The names of the three regions of mesothelial cells that provide protective coating are 1) pleura, the sac which surrounds the lungs; 2) peritoneum, the lining which protects the abdominal cavity; and 3) pericardium, the sac which surrounds the heart. Three different types of mesothelioma cancer attack these three different regions.
Pleural mesothelioma: A type of lung cancer which attacks the pleura surrounding the lungs, this is the most common type of mesothelioma, affecting approximately two-thirds of all mesothelioma patients. Symptoms include horseness, fever, blood in sputum, swollen arms and face, coughing, loss of weight, difficulty breathing, chest pain, weak muscles, and reduced tactile sensitivity.
Peritoneal mesothelioma: A cancer of the abdomen which attacks the peritoneum lining the abdominal cavity. This affects approximately one-third of all mesothelioma patients. Symptoms include abdominal bloating, impaired bowl function, fever, swollen feet, and nausea.
Pericardial mesothelioma: This form of mesothelioma which attacks the pericardium surrounding the heart is extremely rare. Symptoms include chest pain, dyspnea, cough, and palpitations.
Mesothelioma has been linked to asbestos exposure. Asbestos is a type of building material used in thermal insulation products and ceiling tiles. In the United States, asbestos usage peaked during the 1950s - 1970s. During the late 1960s, concerns over the health consequences of asbestos exposure began to arise, thereby decreasing the amount of asbestos manufactured in next two decades. By the 1980s, a new industry of asbestos abatement began to flourish. But according to the United States Environmental Protection Agency (EPA), as many as 733,000 schools and public buildings still contain asbestos.
Small asbestos fibers that enter the air do not evaporate and can remain suspended in the air for a long time. These fibers, when breathed into the body, are toxic. There are three types of asbestos exposure.
Occupational asbestos exposure: People working in factories that manufacure asbestos are likely to have a high exposure to asbestos and are most at risk of developing asbestosis or mesothelioma.
Paraoccupational asbestos exposure: Family members of workers exposed to asbestos in the workplace are susceptible to exposure from asbestos dust brought home by the worker on his clothes or skin.
Neighborhood asbestos exposure: Those who live in the vicinity of an asbestos manufacturing plant are also at risk.
Mesothelioma is still a relatively rare form of cancer. There are an estimated 2,000 - 3,000 new cases per year in the United States. Approximately 7-13 per one million male patients with a history of asbestos exposure contract mesothelioma. Diagnosis usually occurs 20-40 years after initial exposure to asbestos.

By Amie Perlowski
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Early Diagnosis Is Critical For Effective Treatment of Mesothelioma

Cancer is one of the most fatal diseases nowadays. It doesn’t choose its victims. Men and women alike, old and young die of cancer. Mesothelioma is a rare form of cancer that affects the mesothelium, specifically the Pleura (membrane that surrounds the lungs) and the Peritoneum (membrane surrounding the abdomen). Both Pleural Mesothelioma and Peritoneum Mesothelioma are primarily caused by the inhalation or exposure to asbestos, an incombustible fibrous mineral of impure magnesium silicate used in various industrial products. About 30 to 50 per cent of the total Mesothelioma cancer patients had not been exposed to asbestos, yet they have acquired the disease. Cancer specialists continue to study this rare kind of cancer so as to provide the public clear and exact information with regard to its cause, nature and cure.
Like many other forms of cancer, Mesothelioma has different stages. The earliest stage is still curable since only one layer of the pleura is affected. Surgery is the number one option for patients with Stage I Mesothelioma. The doctor removes the part of the lining of the lungs or chest (in case of Pleural Mesothelioma) and the lining of the abdomen (in case of Peritoneal Mesothelioma). In Stage II Mesothelioma, surgery can still be executed although some lymph nodes may have already been infected by the malignant Mesothelioma cancer cells. The diaphragm may also be removed; in severe cases, the Mesothelioma patient has to sacrifice one of his lungs.
Usually, surgery comes with systemic treatments, which include radiotherapy and chemotherapy. Through radiotherapy, Mesothelioma cancer cells are killed; however, only the cells in the treated area die. High energy rays used in radiotherapy or radiation therapy may either come from an external machine or from thin plastic tubes positioned into the tissues where Mesothelioma cancer-stricken cells are found. Inside the plastic tubes are radiation-emitting materials that kill the malignant cells. The use of an external machine is called external radiation therapy while the other is called internal radiation therapy. Also, a radioactive substance such as radiolabeled monoclonal antibody is circulated around the body during radiotherapy.
Chemotherapy is the use of anti-cancer drugs to kill the malignant cells. In treating Mesothelioma, the anti-cancer drugs are usually given to the patient through intravenous injection (within the vein). Oncologists are still studying the possibility of treating Mesothelioma through intracavitary chemotherapy (within the chest or abdomen). Some Mesothelioma patients also undergo Photodynamic therapy, a kind of cancer therapy that combines the use of drug (photosensitizer) with a specific kind of light. The photosensitizing agent when exposed to the light produce oxygen that destroys nearby malignant cancer cells. The drug is injected into the bloodstream and is absorbed by the cells.
In order to relieve the symptoms of Mesothelioma such as the pain in the chest or abdomen due to the build up of fluid, a physician drains the fluid by using a needle. The procedure is known as thoracentesis (removal of fluid in the chest) or paracentesis (removal of the fluid in the abdomen). To prevent further accumulation of the lubricating fluid in the membranes of the chest or abdomen, drugs are given through a tube in the affected organ.
Although the said treatments to Mesothelioma have been proven effective, chance of recovery and survival still depends on the size or extent of the cancer. Chances are higher when Mesothelioma is still in its early stages. Surgery is only advisable only up to the second stage of the Mesothelioma cancer wherein only one part or smaller portions of the membranes are affected. A patient diagnosed with stage IV Mesothelioma (diffuse Mesothelioma) has only about 4-24 months to live. Furthermore, the age of the patient and his general health condition is also crucial to his recovery. Older patients do not respond well to certain cancer treatments such as surgery because their tissues, organs and other body parts are more delicate.

By David Arnold Livingston

Asbestos and Cancer

If you or a loved one has been diagnosed with mesothelioma or another asbestos related cancer, you may want to seek legal advice. Typical legal settelements can reach five million dollars.
Mesothelioma is a rare form of cancer in which malignant (cancerous) cells are found in the mesothelium, a protective sac that covers most of the body's internal organs. Most people who develop mesothelioma have worked on jobs where they inhaled asbestos particles.
What is the mesothelium?
The mesothelium is a membrane that covers and protects most of the internal organs of the body. It is composed of two layers of cells: One layer immediately surrounds the organ; the other forms a sac around it. The mesothelium produces a lubricating fluid that is released between these layers, allowing moving organs (such as the beating heart and the expanding and contracting lungs) to glide easily against adjacent structures.
The mesothelium has different names, depending on its location in the body. The peritoneum is the mesothelial tissue that covers most of the organs in the abdominal cavity. The pleura is the membrane that surrounds the lungs and lines the wall of the chest cavity. The pericardium covers and protects the heart. The mesothelial tissue surrounding the male internal reproductive organs is called the tunica vaginalis testis. The tunica serosa uteri covers the internal reproductive organs in women.
What is mesothelioma?
Mesothelioma (cancer of the mesothelium) is a disease in which cells of the mesothelium become abnormal and divide without control or order. They can invade and damage nearby tissues and organs. Cancer cells can also metastasize (spread) from their original site to other parts of the body. Most cases of mesothelioma begin in the pleura or peritoneum.
How common is mesothelioma?
Although reported incidence rates have increased in the past 20 years, mesothelioma is still a relatively rare cancer. About 2,000 new cases of mesothelioma are diagnosed in the United States each year. Mesothelioma occurs more often in men than in women and risk increases with age, but this disease can appear in either men or women at any age.
What are the risk factors for mesothelioma?
Working with asbestos is the major risk factor for mesothelioma. A history of asbestos exposure at work is reported in about 70 percent to 80 percent of all cases. However, mesothelioma has been reported in some individuals without any known exposure to asbestos.
Asbestos is the name of a group of minerals that occur naturally as masses of strong, flexible fibers that can be separated into thin threads and woven. Asbestos has been widely used in many industrial products, including cement, brake linings, roof shingles, flooring products, textiles, and insulation. If tiny asbestos particles float in the air, especially during the manufacturing process, they may be inhaled or swallowed, and can cause serious health problems. In addition to mesothelioma, exposure to asbestos increases the risk of lung cancer, asbestosis (a noncancerous, chronic lung ailment), and other cancers, such as those of the larynx and kidney.
Smoking does not appear to increase the risk of mesothelioma. However, the combination of smoking and asbestos exposure significantly increases a person's risk of developing cancer of the air passageways in the lung.

By Karen Brown

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Catching a Killer - New Steps Taken in Treating Mesothelioma

There’s a silent killer out there. It creeps up on its victims, attacks them quietly and unsuspectingly, and initiates a wound that develops over many years before it eventually causes pain. This unstoppable murderer is known as mesothelioma.
Mesothelioma is a malignant tumor that develops on the mesothelial cells of either the lungs, heart or abdominal organs, and plagues those who have been exposed to asbestos for a prolonged period of time. Many who fall victim to this disease are people who have worked in specific trades or fields prior to the 1970s, such as blacksmiths, electricians, millwrights, and oil refinery workers.
Since it can take up to forty years for symptoms to surface, mesothelioma-related deaths are higher than ever in the 21st century. The Centers for Disease Control and Prevention state that 1,493 people died from asbestos in 2000, compared to 77 people in 1968.
Mesothelioma treatment methods differ depending on the stage of the cancer upon detection, as well as the patient’s age and personal choice of treatment. The four distinct stages of the disease are a factor in determining the type of mesothelioma treatment that can be carried out. The first stage is when the tumor has had limited growth on the pleural lining (the lining of the lungs). At this stage, an attempt can be made to surgically remove the entire tumor. However, if the tumor is detected at a later stage when it has invaded surrounding areas, it is considered incurable.
Traditionally, the later stages of mesothelioma have been treated with either chemotherapy or radiation therapy. Chemotherapy uses drugs to kill cancer cells while radiation therapy uses high-energy x-rays to kill cancer cells and shrink tumors.
Although mesothelioma treatment methods have been proven to prolong patients’ lives, they cannot cure the disease. Ongoing clinical trials are dedicated to overcoming this debilitating illness. Current experimental treatments include the following:
Drug Therapy: A drug called Alimta, developed by Eli Lilly, has been shown to significantly increase the life expectancy of patients and decrease symptoms of the disease. It is the only chemotherapy drug to be approved by the Food and Drug Administration for the treatment of patients with malignant pleural mesothelioma.
Gene Therapy: This mesothelioma treatment is currently in the experimental stages. The process involves inserting a "suicide gene" directly into the tumor. This gene makes the cells sensitive to a normally ineffective drug called glanciclovir which destroys all the cancer cells and leaves the healthy cells unharmed.
Photodynamic Therapy: Still in its experimental stage, photodynamic therapy uses light to kill cancerous cells. The patient first receives a photosensitizer that only collects in cancerous cells. Fiberoptic cables are then placed in the body in order to focus the right frequency of light on the tumor. The photosensitizer is then caused to produce a toxic oxygen molecule that kills the cancer cell.
Immunotherapy: Also referred to as biological therapy, this mesothelioma treatment uses the body's personal immune system to defend itself against mesothelioma. It has been discovered that the immune system is capable of deciphering healthy cells from cancerous cells, and can thus eradicate those cells that cause cancer.
While treatment methods are still in the developmental or experimental stages, there is hope that one day all mesothelioma victims will be freed from the murderous hands of this fearsome disease.

Avoid Further Mesothelioma Injury Through Prompt Treatment

Mesothelioma injury can be classified into three main groups, Pleural (chest), Peritoneal (abdominal) and Pericardial (heart). All three types of Mesothelioma injury are mainly cause through exposure to an Asbestos related substance.

Mesothelioma injury arises when the Mesothelioma cells surrounding the lungs, heart, or abdominal organs become cancerous. The Mesothelioma cells change to form nodules, which can then clump together to form a tumor, or tumors around the organ.

In more extreme cases of Mesothelioma Cancer, the Mesothelioma tumor can break through the walls of the organs that it surrounds and cause internal damage to the organ. Also, in some cases the Cancer can travel through the blood stream and affect other organs, not directly surrounded by the original Mesothelioma Cancerous Cells.

The origins of Mesothelioma injury begin when a person is exposed to an asbestos related substance. The person either inhales the Asbestos fibers, or the fibers enter the skin. These fibers either lodge in the lungs, or travel through the body and affect the heart, or abdominal organs.

The bodies natural defense system will attempt to eradicate the fibers from the body, through attempts to expel the fibers. However, some fibers will become lodged in the Mesothelioma cell layers that provide a protective layer around the lungs, heart and abdominal area.

Over time, the Mesothelioma cells surrounding the fibers, can change consistency and become cancerous. It is at this stage that the Mesothelioma injury begins to occur, as it turns into Mesothelioma.

However, Mesothelioma injury also includes the conditional affects that occur as a result of having Mesothelioma Cancer. Some of these conditional affects include, immune deficiency, which can lead to a slow break down of the bodies defense system.

Once the bodies defense system begins to break down the body can become subject to colds and other such illnesses. The overall affects of having Mesothelioma Cancer can lead to an array of Mesothelioma injuries and has the potential to cause major organ failure.

In order to prevent the adverse affects of Mesothelioma injury, Mesothelioma doctors have been implementing various treatments that aim to prevent further damage. Some of these treatments include, surgery, chemotherapy, radiation therapy and immune augmentative therapy.

In regard to Mesothelioma Cancer, Surgery aims to remove the Cancerous Mesothelioma cells, while chemotherapy uses drugs to kill the Cancerous cells. Radiation therapy also aims to eliminate the Mesothelioma cells, while immune augmentative therapy aims to restore the body’s natural immune system to a level in which it can be effective in helping to fight the effects of Mesothelioma Cancer.

All of these treatment methods are aimed at preventing further Mesothelioma injury to the patient. If you, or someone you know, have been diagnosed with Mesothelioma Cancer, ensure that you seek immediate treatment to prevent the affects of Mesothelioma Cancer and to avoid further Mesothelioma injury.


By Peter Lenkefi
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Choosing a Mesothelioma Doctor

Mesothelioma Cancer is considered, within the medical profession, to be a serious illness. Mesothelioma Doctors are now available to those who are sufferers of Mesothelioma Cancer.

Mesothelioma Doctors are well educated in the cause of Mesothelioma Cancer, diagnosis of Mesothelioma Cancer, the affects of Mesothelioma Cancer and the available treatment for Mesothelioma Cancer.

Therefore, when choosing a Mesothelioma Doctor, ensure that they have expertise, or quality experience in the area of Mesothelioma Cancer. This can be achieved through your general GP’s general enquiries on your behalf, or through conducting your own research.

You might even consider making enquiries with the American Cancer Society, who hold a variety of information about different types of Cancer and where to seek help. When seeking help it is best to research all your available options and then choose the best one for you.

Some of the important information that you might need to tell your Mesothelioma Doctor include, what types of symptoms you are experiencing, how long ago since you were exposure to an Asbestos related substance and for how long where you exposed to the Asbestos related substance.


After you receive and initial consultation from your Mesothelioma Doctor, you may be required to undergo either a Chest CT scan, or a biopsy, depending on which type of Mesothelioma Cancer your Mesothelioma Doctor considers that you have.

Essentially, there are three possible types of Mesothelioma Cancer that you could have. These include, Pleural (Lungs) Mesothelioma Cancer, Peritoneal (abdominal) and Pericardial (heart).

Once your Mesothelioma Cancer doctor has made a definitive diagnosis, he/she will then be able to tell you which type of Mesothelioma Cancer you have, at what stage the Mesothelioma Cancer is, whether it has spread to surrounding organs, or whether it is contained within the original area of the diseases initiation.

Your Mesothelioma doctor will then discuss your treatment options in relation to the type of Mesothelioma Cancer that you have and what stage the Cancer is at. Your Mesothelioma Doctor should explain these options in detail, including any side affects and the recovery period.

Your Mesothelioma Doctor should also explain to you what the results of not undergoing these recommended treatment options could be. Essentially, your Mesothelioma Doctor should give you a detailed explanation of your entire prognosis.

Your prognosis should include details regarding any risks that you may be subjected to, the chances of the Cancer reoccurring following treatment and how long you are expected to survive once treatment has been implemented.

Keep in mind that through ongoing research into Mesothelioma Cancer, treatments are becoming more effective and patients diagnosed with Mesothelioma Cancer, who undergo treatment, are surviving for longer periods of time.

By Peter Lenkefi
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Asbestos Related Diseases

Asbestos is used in over 3000 modern products and most people have suffered at least some degree of exposure to it at one point or another. Most asbestos exposure is limited to minute portions of well maintained building materials such as concrete, insulation and siding. Regular maintenance of these materials is important for preventing asbestos from degenerating into airborne fibers. Unfortunately, because asbestos is so widespread, it is impossible to compute the damage that even a small quantity can cause.

The lightweight nature of the asbestos particle facilitates airborne spreading of these deadly carcinogens. This is why most asbestos-related diseases affect the respiratory system. These are incurable diseases. Even tiny amounts of asbestos can inflict irreversible damage as symptoms usually only emerge 20 to 30 years down the road.

Mesothelioma, Asbestosis and lung cancer are consequences of prolonged asbestos exposure. Any contact with asbestos merits immediate medical consultation because treatment options and survival rates are greatly improved the earlier they’re detected. Unfortunately most asbestos-related conditions don’t show symptoms until the disease is terminally advanced. Most patients diagnosed with an asbestos-related condition rarely survive more than 18 months after diagnosis.

By T.Going

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